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Updated: Jun 24, 2026
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Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing
Cristina Chamorro1, John A W Kruijtzer, Marina Farsaraki
1Medicinal Chemistry & Chemical Biology, Utrecht Institute of Pharmaceutical Sciences, Faculty of Science, Utrecht University, P.O. Box 80082, NL-3508 TB, Utrecht, The Netherlands.
Chemical Communications (Cambridge, England)
|March 27, 2009
Abstract:
In this Communication, the access to three different peptide loops attached to a small triazacyclophane (TAC) scaffold molecule for the mimicry of discontinuous epitopes present in, for example, antibodies is described for the first time.
