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Procedure for Fabricating Biofunctional Nanofibers
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Published on: September 10, 2012

Preparation and characterization of helical self-assembled nanofibers

Cameron C Lee1, Christophe Grenier, E W Meijer

  • 1Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.

Chemical Society Reviews
|March 27, 2009
PubMed

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Formation of Intermediate Filaments00:57

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Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two cytoskeletal proteins, intermediate filament formation lacks the enzymatic activity to hydrolyze nucleotides like ATP and GTP to generate energy for polymerization. Therefore, the formation of intermediate filaments is multistep self-assembly. The involvement of any accessory proteins in intermediate filament formation has not yet been reported.