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Updated: Jun 24, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Craniofacial growth patterns in patients with congenitally missing permanent teeth
Natascha Bauer1, Katinka Heckmann, Andrea Sand
1Private Orthodontic Practice, Brauerstr. 8, 66663 Merzig/Saar, Germany. Dr.N.Bauer@gmx.de
This study found no significant link between congenitally missing teeth and craniofacial growth patterns. However, horizontal growth was more common in patients missing second premolars.
Area of Science:
- Orthodontics
- Craniofacial Biology
- Genetics
Background:
- Congenital tooth agenesis is a common dental anomaly.
- Understanding its association with craniofacial development is crucial for diagnosis and treatment.
Purpose of the Study:
- To investigate correlations between specific congenitally missing permanent teeth and craniofacial growth patterns.
- To compare cephalometric data of patients with missing teeth to control groups.
Main Methods:
- Lateral cephalograms of 101 patients with congenitally missing teeth were analyzed.
- Cephalometric data included angles (GntgoAr, NSBa, ML-NSL, NL-NSL, MLNL) and facial height indices.
- Patients were grouped by missing teeth: all (A), second premolars (P), upper lateral incisors (S), and various (X). Control groups were used for comparison.
Main Results:
- Overall, patients showed an even distribution of vertical, neutral, and horizontal growth patterns.
- A horizontal growth pattern was more frequent in patients missing second premolars (40.8%).
- No significant correlations were found between missing teeth types and growth patterns in groups S and X. Control groups showed smaller gonial and basal plane angles compared to groups A, P, and S.
Conclusions:
- No statistically significant correlation exists between craniofacial growth patterns and the congenital absence of permanent teeth.
- A trend towards horizontal growth was observed in patients with missing second premolars, though not statistically significant.
- Further research may clarify subtle associations and clinical implications.
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