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Updated: Jun 24, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Hyperammonemic coma presenting as Hashimoto's encephalopathy.

Sweta Adatia¹, B Poladia, S R Joshi

¹Department of Neurology, Lilavati Hospital and Research Center, Bandra (West), Mumbai 400 050.

The Journal of the Association of Physicians of India

|March 28, 2009

Summary

Hyperammonemia with normal liver function can indicate hypothyroidism. Diagnosing Hashimoto

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Last Updated: Jun 24, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Area of Science:

Neurology and Endocrinology
Metabolic Disorders

Background:

Hyperammonemia is frequently observed in patients with active liver disease.
Evaluating hyperammonemia in patients with normal liver function presents diagnostic challenges.

Observation:

A case of undiagnosed hyperammonemic coma with normal liver function was presented.
The patient was diagnosed with Hashimoto's encephalopathy.

Findings:

Hypothyroidism should be investigated in patients presenting with hyperammonemia and normal hepatic function.
Hashimoto's encephalopathy is an underdiagnosed condition that can cause hyperammonemia.

Implications:

Consider Hashimoto's encephalopathy in cases of unexplained coma, especially when hyperammonemia is present without liver dysfunction.
Early diagnosis and treatment of Hashimoto's encephalopathy are crucial for managing hyperammonemic coma.