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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
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[Congenital epulis].

H Braga-Tavares1, H Santos, I M-Pinto

  • 1Unidad de Cirugía Pediátrica, Centro Hospitalar Vila Nova de Gaia/Espinho, EPE. hugotavares@net.sapo.pt

Cirugia Pediatrica : Organo Oficial De La Sociedad Espanola De Cirugia Pediatrica
|March 28, 2009
PubMed
Summary
This summary is machine-generated.

Congenital epulis, a rare benign tumor, typically presents as a gingival mass at birth. Surgical removal offers an excellent prognosis and cosmetic outcome for this condition.

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Area of Science:

  • Oral Pathology
  • Pediatric Dentistry
  • Oncology

Background:

  • Congenital epulis, also known as gingival granular cell tumor, is a rare benign oral tumor.
  • It typically presents as a pediculated mass on the maxillary gingiva in newborns.

Observation:

  • This case report details a specific instance of congenital epulis.
  • The tumor is characterized by its congenital presentation and location.

Findings:

  • While spontaneous regression is documented in some cases, surgical excision is the standard treatment.
  • Histopathological examination confirms the diagnosis of a benign granular cell tumor.

Implications:

  • Early diagnosis and surgical intervention lead to excellent prognoses and satisfactory cosmetic results.
  • Understanding congenital epulis is crucial for pediatric dentists and oral surgeons managing neonatal oral masses.