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Helicobacter pylori infection in Iranian children with recurrent abdominal pain

Nahid Masoodpoor1, Darakhshan, Mehrdad Sheikhvatan

  • 1Department of Paediatrics, Rafsanjan, University of Medical Sciences, Rafsanjan, Iran. swt_f@yahoo.com

Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation
|March 28, 2009
PubMed

Insights

Helicobacter pylori (H. pylori) infection was investigated as a cause of recurrent abdominal pain (RAP) in Iranian children. The study found no significant relationship between H. pylori infection and RAP in this age group.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases

Background:

  • Recurrent abdominal pain (RAP) is a common pediatric issue.
  • The role of Helicobacter pylori (H. pylori) infection in pediatric RAP remains unclear.

Purpose of the Study:

  • To investigate the association between H. pylori infection and RAP in Iranian children.
  • To determine if H. pylori is a causative agent for RAP in pediatric patients.

Main Methods:

  • A case-control study involving 40 children with RAP and 60 healthy controls (ages 12-15).
  • Demographic and clinical data collected via questionnaires and physical examination.
  • Stool antigen testing (HpSA ELISA) performed on all participants.

Main Results:

  • H. pylori infection was detected in 16 of 40 children with RAP.
  • H. pylori infection was detected in 15 of 60 healthy children.
  • No statistically significant relationship was found between H. pylori infection and RAP (p=0.112).

Conclusions:

  • The prevalence of H. pylori infection is similar in children with and without RAP.
  • H. pylori infection is unlikely to be a primary cause of RAP in Iranian children aged 12-15.
  • Further research may be needed to explore other etiologies of pediatric RAP.
Abstract

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