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Androgenic alopecia and insulin resistance: are they really related?
L Nabaie1, S Kavand, R M Robati
1Skin Research Centre, Shahid Beheshti University, M.C. Shohada-e Tajrish Hospital, Tehran, Iran.
Background:
Androgenic alopecia is known to be androgen-dependent. Insulin is found in hair follicles and may play a role in the regulation of androgen metabolism and the hair-growth cycle.
Objectives:
To compare the insulin resistance between people with androgenic alopecia and a control group.
Methods:
A case-control study was conducted with 97 cases in the patient and 87 in the control group. Serum fasting insulin level, fasting blood glucose, serum total cholesterol, triglyceride and high-density lipoprotein (HDL) were all measured in both groups.
Results:
There was no difference in serum fasting insulin level, fasting blood glucose, serum total cholesterol, triglyceride, HDL and insulin resistance between the two groups (P > 0.05).
Conclusion:
Despite previous reports suggesting a link, our study found no significant relationship between insulin resistance and androgenic alopecia. Further studies are warranted.
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