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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Rh Blood Group01:19

Rh Blood Group

The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

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Related Experiment Video

Updated: Jun 24, 2026

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
07:57

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin

Published on: August 25, 2022

Transfusion therapy in postpartum hemorrhage.

Anand Padmanabhan1, Joseph Schwartz, Steven L Spitalnik

  • 1The Section of Transfusion Medicine and Cell Therapy, Department of Pathology and Cell Biology, Columbia University Medical Center, College of Physicians and Surgeons of Columbia University, New York, NY, USA.

Seminars in Perinatology
|March 28, 2009
PubMed
Summary

Postpartum hemorrhage (PPH) is a critical obstetric emergency. Prompt diagnosis and management with blood components, considering ratios and disseminated intravascular coagulation (DIC), are vital for maternal and fetal outcomes.

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Published on: March 14, 2017

Area of Science:

  • Obstetrics and Gynecology
  • Hematology
  • Critical Care Medicine

Background:

  • Postpartum hemorrhage (PPH) is a leading cause of maternal mortality worldwide.
  • Effective management of PPH requires rapid diagnosis and timely intervention.
  • Traditional management relies on blood component therapy, but newer strategies are emerging.

Purpose of the Study:

  • To review the current understanding and management strategies for postpartum hemorrhage.
  • To highlight the importance of rapid diagnosis and the use of blood components in defined ratios.
  • To discuss the role of newer hemostatic agents and obstetric bleeding protocols.

Main Methods:

  • Literature review of recent studies on PPH management.
  • Analysis of laboratory and clinical parameters for PPH diagnosis.
  • Evaluation of traditional and novel hemostatic agents.

Main Results:

  • Rapid diagnosis of PPH is crucial for effective management.
  • Transfusion of blood components (RBCs, platelets, plasma, cryoprecipitate) in defined ratios can prevent dilutional coagulopathy.
  • Disseminated intravascular coagulation (DIC) requires aggressive treatment with blood components.
  • Newer agents like activated factor VII show promise for refractory bleeding.

Conclusions:

  • An integrated obstetric bleeding protocol incorporating updated coagulation knowledge is recommended.
  • This protocol can improve outcomes for mothers and fetuses experiencing PPH.
  • Early and appropriate use of blood products and novel agents is key to managing severe PPH.