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Cooperative Allosteric Transitions

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Related Experiment Video

Updated: Jun 24, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Temporal mechanisms of multimodal binding.

David Burr1, Ottavia Silva, Guido Marco Cicchini

  • 1Department of Psychology, Università Degli Studi di Firenze, via S. Nicolò 89, Florence 50125, Italy. dave@in.cnr.it

Proceedings. Biological Sciences
|March 28, 2009
PubMed
Summary

Humans perceive time by integrating signals from different senses. This study found that our brains are slower at processing simultaneous auditory-visual information compared to information from a single sense, impacting temporal perception.

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Area of Science:

  • Neuroscience
  • Psychology
  • Sensory Perception

Background:

  • The brain uses sensory simultaneity to identify environmental sources.
  • Understanding sensory integration mechanisms is crucial for explaining temporal perception.

Purpose of the Study:

  • To investigate human sensory mechanisms for assessing signal simultaneity.
  • To measure discrimination thresholds for auditory, visual, and cross-modal stimuli.

Main Methods:

  • Participants discriminated time intervals using auditory, visual, or combined auditory-visual stimuli.
  • Discrimination thresholds were measured across various base interval durations.
  • A computational model with temporal filters was developed to simulate human performance.

Main Results:

  • Discrimination thresholds followed a 'dipper function' across all conditions.
  • Optimal temporal discrimination occurred at non-zero base intervals.
  • Lowest thresholds were observed at ~5 ms (auditory), ~15 ms (visual), and ~75 ms (auditory-visual).

Conclusions:

  • Cross-modal temporal processing is significantly slower than unimodal processing.
  • Temporal filters with varying time constants influence temporal perception.
  • The developed model accurately replicates observed human temporal discrimination functions.