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Updated: Jun 24, 2026

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering
Published on: November 9, 2017
Application of electron paramagnetic resonance spectroscopy for validation of the novel (AN+DN) solvent polarity
Luciana Malavolta1, Erick F Poletti, Elias H Silva
1Department of Biophysics, Universidade Federal de Sao Paulo, SP, Brazil. luciana@biofis.epm.br
Abstract:
Based on solvation studies of polymers, the sum (1:1) of the electron acceptor (AN) and electron donor (DN) values of solvents has been proposed as an alternative polarity scale. To test this, the electron paramagnetic resonance isotropic hyperfine splitting constant, a parameter known to be dependent on the polarity/proticity of the medium, was correlated with the (AN+DN) term using three paramagnetic probes. The linear regression coefficient calculated for 15 different solvents was approximately 0.9, quite similar to those of other well-known polarity parameters, attesting to the validity of the (AN+DN) term as a novel "two-parameter" solvent polarity scale.
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