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Related Concept Videos

Ethics in Research01:56

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.

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Go3R - semantic Internet search engine for alternative methods to animal testing.

Ursula G Sauer1, Thomas Wächter, Barbara Grune

  • 1Scientific Consultancy - Animal Welfare, Neubiberg/Munich, Germany. ursula.sauer@sauerug.de

ALTEX
|March 28, 2009
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Summary

Go3R is a novel search engine designed to help scientists find alternative methods for animal testing, supporting the replacement, reduction, and refinement principles in research.

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Area of Science:

  • Biomedical research
  • Animal welfare science
  • Information science

Background:

  • EU Directive 86/609/EEC mandates the consideration of alternatives to animal testing.
  • Scientists require accessible information to fulfill legal obligations for animal experiment replacement, reduction, and refinement (3Rs).
  • Current information access for alternative methods is fragmented and lacks standardized services.

Purpose of the Study:

  • To introduce Go3R, a search engine addressing the need for convenient access to information on alternative methods.
  • To facilitate compliance with the 3Rs principle in animal experimentation.
  • To promote the avoidance and replacement of animal experiments through accessible data.

Main Methods:

  • Development of Go3R, a free, web-based search engine (http://Go3R.org).
  • Utilizes semantic technologies and an expert-knowledge based ontology for document identification.
  • Designed for intuitive use without extensive training.

Main Results:

  • Go3R is the first global search engine focused on alternative methods for animal testing.
  • It enables fast, comprehensive, and transparent determination of non-animal methodology availability.
  • The platform supports researchers, ethic committees, and regulatory bodies in planning animal experiments.

Conclusions:

  • Go3R aims to become a standard service for accessing information on alternative research methods.
  • The search engine significantly contributes to the practical implementation of the 3Rs principle.
  • Go3R supports the scientific community in reducing and replacing animal use in research.