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Related Experiment Video

Updated: Jun 24, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
08:17

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Published on: September 22, 2017

Ollier disease.

Luca D'Angelo1, Luca Massimi, Alessandro Narducci

  • 1Paediatric Neurosurgical Unit, Catholic University of Rome, Rome, Italy. lucadangelo_80@hotmail.com

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|March 28, 2009
PubMed
Summary
This summary is machine-generated.

Ollier disease can cause skull base enchondromas, requiring surgery. Radiation therapy is used when complete tumor removal is not possible or if sarcomatous changes occur.

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Last Updated: Jun 24, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
08:17

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Published on: September 22, 2017

Area of Science:

  • Neurology
  • Oncology
  • Genetics

Background:

  • Ollier disease is a rare nonfamilial disorder causing multiple enchondromas.
  • Intracranial enchondromas can develop at the skull base, leading to headaches and cranial nerve palsy.

Observation:

  • A 12-year-old boy with Ollier disease underwent surgery for a skull base enchondroma.
  • Postoperative imaging revealed residual tumor, necessitating radiation therapy.

Findings:

  • Surgery is the primary treatment for intracranial enchondromas.
  • Radiation therapy is crucial for unresectable tumors or sarcomatous transformation.

Implications:

  • This case highlights the combined surgical and radiological approach for managing complex skull base enchondromas in Ollier disease.
  • Effective management strategies are essential to address complications like pathological fractures and neurological deficits.