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Fluorescent End-Labeling and Encapsulation of Long RNAs for Single-Molecule FRET-TIRF Microscopy
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Synthesis and characterization of circular structures of i-motif tagged with fluoresceins
Tianyan Zhou1, Xinming Li, Magdeline Tao Tao Ng
1Peking University, Beijing, The People's Republic of China.
Bioconjugate Chemistry
|March 31, 2009
Abstract:
Synthesis of a fluorescein-tagged circular structure of i-motif was accomplished during our investigations. The backbone circularity of this molecular probe and the presence of the fluorescent moiety within its structure were also confirmed through exonuclease hydrolysis and fluorescence spectroscopy.
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