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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...

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Related Experiment Video

Updated: Jun 24, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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New stent design for percutaneous aortic valve replacement.

Gideon V Praveen Kumar1, Lazar Mathew

  • 1School of Biotechnology, Chemical and Biomedical Engineering, VIT University, Vellore, India. gidi99_5611@yahoo.co.in

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|March 31, 2009
PubMed
Summary

New vascular support structures, or stents, offer a cost-effective and minimally invasive treatment for valve stenosis. This study details the design of a novel stent, crucial for improving patient outcomes and reducing healthcare costs.

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Last Updated: Jun 24, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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Published on: June 8, 2022

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Cardiovascular Research

Background:

  • Vascular support structures are vital for treating valve stenosis.
  • Percutaneous valvuloplasty is a primary treatment for valvular disease.
  • Stent devices represent an advanced and increasingly adopted treatment modality, especially in Europe.

Purpose of the Study:

  • To describe the design of a novel vascular support structure (stent).
  • To provide designers with critical parameter estimates for stent development.
  • To support the design process where in vivo experimentation is challenging.

Main Methods:

  • Focus on the design of a new vascular support structure.
  • Utilizing structural analysis for critical parameter estimation.
  • Considering stainless steel as a preferred material for balloon-expanded prostheses.

Main Results:

  • The design aims to offer highly effective results.
  • The new technology is associated with minimal cost and reduced hospital stays.
  • Stainless steel stents are identified as a cost-effective option.

Conclusions:

  • Accurate structural analysis is essential for designing effective vascular support structures.
  • The developed stent design offers a promising alternative for treating valve stenosis.
  • The use of stainless steel enhances the cost-effectiveness of these prostheses.