Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

A Randomized, Double-blind, Placebo-controlled, Dose Ranging, Parallel, Multi-Centre, Phase II Study to Evaluate the Efficacy and Safety of MT921 in Subjects with Moderate to Severe Submental Fat.

Aesthetic surgery journal·2026
Same journal

Treatment Satisfaction, Improvements in Jawline Definition, and Psychosocial Impact With OnabotulinumtoxinA for Platysma Prominence: Patient-Reported Outcomes From 2 Multicenter, Randomized, Placebo-Controlled Phase 3 Studies.

Aesthetic surgery journal·2026
Same journal

Recombinant Humanized Type III Collagen Enhances Fat Graft Retention by Promoting Angiogenesis and Adipocyte Viability in a Nude Mouse Model.

Aesthetic surgery journal·2026
Same journal

Beyond the Fixed Grid: Precision-guided Botulinum Toxin Treatment for Primary Axillary Hyperhidrosis.

Aesthetic surgery journal·2026
Same journal

Buccal Fat Suspension: Not Just a Lift-Restoring the Foundational Anatomy of a Youthful Cheek.

Aesthetic surgery journal·2026
Same journal

Adverse Outcomes and Complications of Autologous Versus Homologous Costal Cartilage Grafts in Septorhinoplasty: A Systematic Review and Meta-analysis.

Aesthetic surgery journal·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
03:47

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Minimizing scars with excision and immediate laser resurfacing.

W A Stefani

    Aesthetic Surgery Journal
    |March 31, 2009
    PubMed
    Summary
    This summary is machine-generated.

    The Ultrapulse carbon dioxide (CO2) laser offers precise skin resurfacing for acne scars. This study shows it effectively treats moderate to severe facial scarring with minimal visible marks.

    More Related Videos

    Apparatus for Harvesting Tissue Microcolumns
    06:06

    Apparatus for Harvesting Tissue Microcolumns

    Published on: October 25, 2018

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
    04:12

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

    Published on: January 19, 2024

    Related Experiment Videos

    Last Updated: Jun 24, 2026

    Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
    03:47

    Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

    Published on: September 27, 2024

    Apparatus for Harvesting Tissue Microcolumns
    06:06

    Apparatus for Harvesting Tissue Microcolumns

    Published on: October 25, 2018

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
    04:12

    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

    Published on: January 19, 2024

    Area of Science:

    • Dermatology
    • Laser Technology
    • Plastic Surgery

    Background:

    • The Ultrapulse carbon dioxide (CO2) laser is a recognized tool for cosmetic skin resurfacing.
    • Traditional methods like peels and dermabrasion lack the precision and depth control offered by laser technology.
    • The epithelial migration healing model suggests that well-aligned wound edges result in reduced scarring.

    Purpose of the Study:

    • To evaluate the efficacy of the Ultrapulse CO2 laser in treating facial lesions and acne scarring.
    • To assess the cosmetic outcome and scarring in patients undergoing laser resurfacing for different grades of acne scars.

    Main Methods:

    • The study included 10 patients with facial lesions and acne scarring, categorized into grades I (mild), II (moderate), and III (severe).
    • Patients with moderate to severe scarring (grades II and III) underwent surgical excision followed by immediate laser resurfacing using the Ultrapulse CO2 laser.
    • The procedure focused on achieving precisely coapted wound margins to promote optimal healing.

    Main Results:

    • The Ultrapulse CO2 laser provided enhanced precision and depth control compared to traditional resurfacing techniques.
    • Patients with moderate to severe acne scarring (grades II and III) treated with excision and laser resurfacing exhibited minimally perceptible scars.
    • The healing process, guided by epithelial migration, resulted in favorable cosmetic outcomes.

    Conclusions:

    • The Ultrapulse CO2 laser is a valuable tool for precise skin resurfacing, particularly for managing facial lesions and acne scarring.
    • Combining excision with immediate laser resurfacing is an effective strategy for treating moderate to severe acne scars, leading to minimal scarring.
    • This laser modality offers superior control and improved aesthetic results in dermatological procedures.