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[Tumor response in comparative trials]
1Département de biostatistique et d'épidémiologie, institut Gustave-Roussy, Villejuif, France.
Bulletin Du Cancer
|January 1, 1991
Abstract:
Survival improvement is the main aim of most cancer trials. Tumor response is a very common end-point in this context, as it permits a quick answer. It is useful criterion for screening in phase II trials, but cannot be utilised in phase III comparative trials for several reasons put forward in this article.