Related Experiment Video
Updated: Jun 24, 2026

Study of Experimental Organ Donation Models for Lung Transplantation
Published on: March 15, 2024
Multiple correspondence analysis in predictive logistic modelling: application to a living-donor kidney
Renan Moritz Varnier R Almeida1, Antonio Fernando C Infantosi, José Hermógenes R Suassuna
1Biomedical Engineering Program - COPPE, Federal University of Rio de Janeiro, P.O. Box 68510, Rio de Janeiro, RJ 21941-972, Brazil. renan@peb.ufrj.br
Abstract:
This work deals with the use of multiple correspondence analysis (MCA) and a weighted Euclidean distance (the tolerance distance) as an exploratory tool in developing predictive logistic models. The method was applied to a living-donor kidney transplant data set with 109 cases and 13 predictors. This approach, followed by backward and forward selection procedures, yielded two models, one with four and another with two predictors. These models were compared to two other models, ordinarily built by backward and forward stepwise selection, which yielded, respectively, five and two predictors. After internal validation, the models performance statistics showed similar results. Likelihood ratio tests suggested that backward approach achieved a better fit than the forward modelling in both methods and the Vuong's non-nested test between backward-built models suggested that these were undistinguishable. We conclude that the tolerance distance, in combination with MCA, could be a feasible method for variable selection in logistic modelling, when there are several categorical predictors.
Related Concept Videos
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
