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Related Concept Videos

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Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
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Related Experiment Video

Updated: Jun 24, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

[Practical means of temperature control].

T Rival1, N Mayeur, V Minville

  • 1Unité d'anesthésie en neurochirurgie, pôle d'anesthésie-réanimation, GRCB 48, hôpital Purpan, CHU de Toulouse, université Paul-Sabatier, place du Docteur-Baylac, 31059 Toulouse cedex 09, France. rival.t@chu-toulouse.fr

Annales Francaises D'Anesthesie Et De Reanimation
|March 31, 2009
PubMed
Summary
This summary is machine-generated.

Mild therapeutic hypothermia offers neuroprotection for conditions like cardiac arrest and neonatal anoxia. Cooling methods include external (ice packs, cooled air) and internal (perfusion, catheters) techniques, alongside medications.

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Area of Science:

  • Medical Science
  • Physiology
  • Neuroscience

Context:

  • Mild therapeutic hypothermia is utilized for neuroprotection in specific clinical scenarios, such as postanoxic cardiac arrest and neonatal anoxia.
  • Effective temperature management is crucial for patient outcomes in critical care settings.

Purpose:

  • To review and categorize the various methods for inducing therapeutic hypothermia.
  • To compare the efficiency and cost-effectiveness of different cooling techniques.

Summary:

  • Therapeutic hypothermia employs thermal exchange principles, primarily conduction and convection.
  • External cooling methods (ice packs, cooled air, circulating mattresses) are cost-effective.
  • Internal cooling techniques (perfusion, catheters, extracorporeal circulation) offer greater efficiency for rapid temperature control.
  • Pharmacological agents can also induce hypothermia or manage shivering, including antipyretics and specific drug classes.

Impact:

  • Understanding diverse hypothermia induction methods aids clinicians in selecting optimal strategies for neuroprotection.
  • This review highlights the trade-offs between cost, efficiency, and invasiveness in therapeutic cooling.
  • Knowledge of pharmacological interventions expands treatment options for managing temperature and shivering.