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Updated: Jun 24, 2026

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection
Published on: August 20, 2007
Immunosuppression and rejection in human hand transplantation
S Schneeberger1, V S Gorantla, T Hautz
1Center of Operative Medicine, Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria. stefan.schneeberger@imed.ac.at
Abstract:
Avoidance or at least minimization of maintenance immunosuppression represents the key step for promoting wider applicability of reconstructive transplantation. Understanding the mechanisms of composite tissue allograft rejection is essential in working toward that goal. We herein review the current knowledge on acute rejection in reconstructive transplantation and discuss findings in the light of novel immunosuppressive and immunomodulatory strategies.
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