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Eye Tracking Young Children with Autism
Published on: March 27, 2012
The early stool patterns of young children with autistic spectrum disorder
1Centre for Child and Adolescent Health, University of Bristol, Bristol, UK.
Insights
Children with autistic spectrum disorder (ASD) showed similar bowel patterns to peers, with no signs of enterocolitis. A slight increase in stool frequency was noted in ASD children at later ages.
Area of Science:
- Pediatric Gastroenterology
- Neurodevelopmental Disorders
- Gastrointestinal Health
Background:
- Autistic spectrum disorder (ASD) is a neurodevelopmental condition.
- Gastrointestinal (GI) issues are frequently reported in children with ASD.
- Enterocolitis, a serious inflammation of the intestines, is a potential concern in children with ASD.
Purpose of the Study:
- To determine if children with autistic spectrum disorder (ASD) exhibit bowel symptoms indicative of enterocolitis.
- To compare the gastrointestinal health of children with ASD to neurotypical children.
Main Methods:
- Utilized data from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort.
- Analyzed stool patterns and gut symptoms via questionnaires from 12,984 children up to 42 months of age.
- Compared 78 children with ASD to 12,906 children without ASD.
Main Results:
- No significant differences in stool color, consistency, or common GI symptoms (diarrhea, constipation, bloody stools, abdominal pain) between ASD and control groups in the first 3.5 years.
- A trend towards increased stool frequency was observed in children with ASD at 30 and 42 months of age.
- Analysis of classical childhood autism cases yielded similar findings.
Conclusions:
- Children with ASD generally present with similar stool patterns to their peers during the first 42 months of life.
- A slight increase in stool frequency at 30 and 42 months was noted in the ASD group.
- The study found no evidence to support the hypothesis that children with ASD experience enterocolitis.
Aim:
To investigate whether children with autistic spectrum disorder (ASD) have bowel symptoms consistent with underlying enterocolitis.
Methods:
Information on children's stool patterns and gut symptoms collected by questionnaire at 4 weeks and at 6, 18, 30 and 42 months of age were available for 12,984 children from the Avon Longitudinal Study of Parents and Children (ALSPAC). Data on the 78 children identified by local health and/or education systems to have special educational provision for ASD were compared with the 12,906 remaining children in the cohort.
Results:
Comparison of the ASD and control group during the first 3.5 years of life showed no major differences in stool colour or consistency, or in frequency of diarrhoea, constipation, bloody stools or abdominal pain. The ASD children had similar stool frequency up to 18 months, but there was a trend for ASD children to pass more stools at 30 months (OR 3.73, 95% CI 1.11 to 12.6; p = 0.004) and at 42 months (OR 6.46, 95% CI 1.83 to 22.7; p<0.001), although only three children passed more than 4 stools/day. Repeating the analysis on only those cases diagnosed as having classical childhood autism resulted in very similar findings.
Conclusions:
During the first 42 months of life, ASD children had a stool pattern that was very similar to that of other children, apart from a slight increase in stool frequency at 30 and 42 months. There were no symptoms to support the hypothesis that ASD children had enterocolitis.
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