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Hyperamylasaemia in ureteric colic
Y A Al-Abed1, K R Ghani, T W Carr
1Southend University Hospital, Prittlewell Chase, Westcliff-on-Sea, SS0 0RY, UK. yalabed@yahoo.co.uk
Postgraduate Medical Journal
|March 31, 2009
Summary
Ureteric colic, a condition typically causing severe pain, can unexpectedly lead to elevated serum amylase levels. This finding suggests a link between urinary extravasation and pancreatic irritation.
Area of Science:
- Nephrology
- Gastroenterology
- Biochemistry
Background:
- Hyperamylasemia is commonly linked to acute pancreatitis.
- However, various other clinical conditions can also elevate serum amylase.
- Ureteric colic has not been previously reported as a cause of hyperamylasemia.
Observation:
- A 47-year-old woman presented with symptoms suggestive of left ureteric colic.
- Radiological imaging revealed an upper ureteric stone with associated urinary extravasation.
- Serum amylase levels were elevated upon presentation but normalized within 24 hours.
Findings:
- This case report documents hyperamylasemia in a patient with ureteric colic.
- The elevated amylase levels normalized spontaneously within 24 hours.
- Urinary extravasation secondary to the ureteric stone is proposed as the cause.
Implications:
- Ureteric colic should be considered as a potential cause of hyperamylasemia.
- Elevated serum amylase in ureteric colic patients may indicate urinary extravasation.
- This association warrants further investigation into the mechanism of pancreatic irritation.
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