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09:12
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Smoking after coronary artery bypass: high three-year mortality
G M Lindsay1, E P Tolmie, W M Martin
1Cardiac Surgery, University of Glasgow, Glasgow, UK.
The Thoracic and Cardiovascular Surgeon
|March 31, 2009
Summary
Persistent smoking negates the long-term survival benefits of coronary artery bypass grafting (CABG). Smokers face accelerated late mortality and increased myocardial ischemia after CABG surgery.
Area of Science:
- Cardiology
- Thoracic Surgery
- Public Health
Background:
- Coronary artery bypass grafting (CABG) improves prognosis and symptoms.
- Smoking's impact on long-term CABG survival remains unclear.
- This study investigates smoking's effect on survival and ischemia 7 years post-CABG.
Purpose of the Study:
- To determine the long-term influence of smoking on survival after CABG.
- To assess the impact of smoking on myocardial ischemia seven years post-CABG.
- To identify other risk factors affecting long-term outcomes after CABG.
Main Methods:
- 208 patients undergoing elective CABG were analyzed.
- 25% of patients were persistent smokers.
- Survival, symptoms, and thallium scans were assessed at 7 years.
Main Results:
- Smokers reported higher rates of angina and dyspnea.
- Smokers exhibited higher stress thallium and ischemia scores.
- Smoking was associated with increased mortality starting at 3 years post-CABG.
Conclusions:
- CABG offers significant benefits, but persistent smoking negates them.
- Smoking accelerates late mortality after CABG, exceeding previous reports.
- Symptoms and perfusion scans indicate higher ischemia in smokers post-CABG.
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