Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Pulmonary Cycle: Exhalation

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The cultural heritage of pastoralism - local knowledge, state identity and the global perspective: the example of local breeds in Morocco.

Revue scientifique et technique (International Office of Epizootics)·2016

Same author

[2014 literature findings in internal general medicine].

Revue medicale suisse·2015

Same author

[Does prematurity affect adulthood?].

Revue medicale suisse·2014

Same author

[Former preterm infant with bronchopulmonary dysplasia: how will this be cared for in 2014?].

Revue medicale suisse·2014

Same author

[Pediatric specialties and collaboration Vaud-Geneva.].

Revue medicale suisse·2011

Same author

[The importance of non-pediatric specialists].

Revue medicale suisse·2010

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

[Childrens' chronic cough revisited].

R Corbelli¹, S Guinand, C Barazzone Argiroffo

¹Unité de pneumologie pédiatrique, Département de l'enfant et de l'adolescent, Hôpital des Enfants, HUG, 1211 Genève 14. regula.corbelli@hcuge.ch

Revue Medicale Suisse

|April 1, 2009

Summary

This summary is machine-generated.

Chronic cough in children often signals a respiratory infection. Early diagnosis and a pediatric-specific approach, including identifying protracted bacterial bronchitis, are crucial to prevent long-term lung issues like bronchiectasis.

More Related Videos

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Related Experiment Videos

Last Updated: Jun 24, 2026

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Area of Science:

Pediatrics
Respiratory Medicine
Infectious Diseases

Context:

Chronic cough is a prevalent symptom in children, frequently linked to respiratory infections.
Distinguishing chronic cough from acute cough (lasting >4-8 weeks) is vital for appropriate management.
Standard adult diagnostic methods are unsuitable for pediatric chronic cough evaluations.

Purpose:

To highlight a specialized pediatric approach for diagnosing prolonged or chronic cough in children.
To emphasize the significance of protracted bacterial bronchitis as a newly recognized airway disease.
To underscore the importance of timely diagnosis and treatment of protracted bacterial bronchitis to prevent complications.

Summary:

This article advocates for age-specific diagnostic strategies in pediatric chronic cough.
It introduces protracted bacterial bronchitis as a key diagnosis to consider in persistent cough.
Adequate management of this condition is essential to avert recurrent infections and bronchiectasis.

Impact:

Promotes accurate diagnosis and effective treatment of chronic cough in pediatric populations.
Aims to reduce the incidence of long-term respiratory sequelae, such as bronchiectasis.
Enhances clinical awareness of protracted bacterial bronchitis, improving patient outcomes.