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Bladder dysfunction due to human T-lymphotrophic virus type I associated myelopathy
British Journal of Urology
|October 1, 1991
Summary
Bladder dysfunction, including urinary retention and incontinence, is common in patients with Human T-lymphotropic virus type I associated myelopathy (HAM). Urodynamic studies reveal detrusor hyper-reflexia or areflexia contributing to these symptoms.
Area of Science:
- Neurology
- Urology
- Virology
Background:
- Bladder dysfunction is a significant complication in Human T-lymphotropic virus type I associated myelopathy (HAM).
- Symptoms include difficulty urinating, frequency, nocturia, and urge incontinence.
Purpose of the Study:
- To investigate the urodynamic findings in patients with HAM-related bladder dysfunction.
- To characterize the patterns of detrusor activity during storage and voiding phases.
Main Methods:
- Urodynamic studies were performed on four patients diagnosed with HAM.
- Evaluation included assessment of bladder sensation, detrusor contractility, and presence of involuntary contractions.
Main Results:
- Three patients experienced significant urinary retention.
- Severe detrusor hyper-reflexia was observed in three patients, while one patient exhibited detrusor areflexia.
- Bladder sensation was preserved in all patients.
Conclusions:
- Urodynamic evaluation is crucial for understanding bladder dysfunction in HAM.
- Both detrusor hyper-reflexia and areflexia contribute to lower urinary tract symptoms in HAM patients.