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Related Concept Videos

Other Disorders of Digestive System01:30

Other Disorders of Digestive System

The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Updated: Jun 24, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Eosinophilic gastrointestinal disorders.

Amal Assa'ad1

  • 1Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA. amal.assa'ad@cchmc.org

Allergy and Asthma Proceedings
|April 1, 2009
PubMed
Summary
This summary is machine-generated.

Eosinophilic gastrointestinal disorders (EGID) are common in atopic patients. Allergists/immunologists play a key role in diagnosing and managing EGID through history, testing, and endoscopic procedures.

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Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
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Last Updated: Jun 24, 2026

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Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
07:41

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice

Published on: February 3, 2016

Area of Science:

  • Allergy and Immunology
  • Gastroenterology
  • Immunopathology

Background:

  • Eosinophilic gastrointestinal disorders (EGID) are frequently seen by allergists/immunologists.
  • Atopy-related genes, inflammatory cells, and mediators are implicated in EGID pathogenesis.
  • EGID often occur in atopic individuals.

Purpose of the Study:

  • To provide a practical approach for allergists/immunologists in identifying and managing EGID.
  • To highlight the role of allergists/immunologists in the diagnostic and therapeutic process of EGID.

Main Methods:

  • Diagnosis involves patient history to elicit symptoms and define the atopic phenotype.
  • Allergen identification through skin testing and patch testing.
  • Tissue diagnosis via esophagogastroduodenoscopy is essential.

Main Results:

  • Diagnostic strategies include clinical evaluation and endoscopic procedures.
  • Treatment options encompass topical steroids, dietary modifications, and novel agents like anti-IL-5 monoclonal antibodies.
  • EGID management requires long-term follow-up due to the chronic, relapsing nature of the disorders.

Conclusions:

  • Allergists/immunologists are central to the diagnosis, treatment, and management of EGID.
  • A comprehensive approach integrating clinical assessment, diagnostic testing, and therapeutic interventions is crucial.
  • Understanding the chronic course of EGID is vital for effective patient care.