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Related Experiment Video

Updated: Jun 24, 2026

Molecular Evolution of the Tre Recombinase

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

[Evolutionary medicine: the future looking at the past].

Serafim Carvalho¹, Margarida Rosado

¹Hospital de Magalhães Lemos, Porto.

Acta Medica Portuguesa

|April 1, 2009

Summary

Evolutionary medicine explains health and disease as mismatches between our ancient genes and modern lifestyles. This perspective helps identify vulnerabilities and improve prevention and treatment strategies.

Area of Science:

Evolutionary medicine
Basic science
Human health and disease

Context:

Modern lifestyles create a mismatch with the human environment of evolutionary adaptation.
Contemporary human genomes and phenotypes are Palaeolithic, not adapted to modern life.
This evolutionary gap contributes to "diseases of civilization".

Purpose:

To understand the importance of evolutionary theories in health and disease concepts.
To provide new insights into medical investigation and practice.
To review existing literature on evolutionary medicine.

Summary:

Human health and disease are viewed through the lens of evolutionary mismatch.
Ancient genetic predispositions interact with modern environments, leading to maladaptation.

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Last Updated: Jun 24, 2026

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Published on: September 20, 2016

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Excessive evolutionary strategies can manifest as emotional and behavioral disorders.

Impact:

Evolutionary medicine enhances the detection of human vulnerabilities and maladaptations.
It offers a novel framework for disease prevention and treatment.
This approach reframes understanding of "diseases of civilization" and their origins.