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Updated: Jun 24, 2026
10:43
Rapid and Low-cost Prototyping of Medical Devices Using 3D Printed Molds for Liquid Injection Molding
Published on: June 27, 2014
Summary
Practitioners use unapproved liquid silicone oil for cosmetic purposes. A clinical study is now investigating injectable silicone oil for soft tissue augmentation, providing historical context for this off-label application.
Area of Science:
- Plastic Surgery
- Ophthalmology
- Biomaterials
Background:
- Liquid silicone oil is FDA-approved for retinal detachment treatment.
- Its off-label use for cosmetic indications is prevalent in the US.
- This practice raises safety and regulatory concerns.
Purpose of the Study:
- To discuss the off-label use of liquid silicone oil for aesthetic purposes.
- To provide historical context for injectable silicone oil in soft tissue augmentation.
- To highlight the current FDA-approved clinical study.
Main Methods:
- Review of off-label injection practices.
- Historical analysis of silicone use in cosmetic procedures.
- Discussion of regulatory status and clinical trials.
Main Results:
- Liquid silicone oil is being used cosmetically despite lack of FDA approval for such indications.
- A clinical study is underway to evaluate injectable silicone oil for soft tissue augmentation.
- The historical context reveals a pattern of exploring silicone for aesthetic enhancement.
Conclusions:
- The off-label use of liquid silicone oil for cosmetic purposes is a significant concern.
- Ongoing clinical studies aim to establish the safety and efficacy of injectable silicone oil for augmentation.
- Regulatory oversight and approved indications remain critical for patient safety.
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