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Updated: Jun 24, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Primary extrauterine endometrial stromal cell sarcoma: a case and review
Alla Zemlyak1, Sonya Hwang, Eva Chalas
1Stony Brook University Medical Center, Stony Brook, NY, USA.
Background:
Extrauterine endometrial stromal sarcoma (ESS) is a rare neoplasm. Little is known about its pathophysiology or best treatment approach.
Case:
We are describing a case of extrauterine ESS in a 70-year-old woman on hormone replacement therapy and with a history of endometriosis. We also present a brief review of the literature on ESS and its relationship to endometriosis and hormonal therapy.
Conclusions:
Complete resection should remain the treatment of choice for ESS. Unresectable or metastatic low-grade ESS may respond well to progestin therapy, but outcomes of high-grade ESS tend to be poor.
