Related Experiment Video
Updated: Jun 24, 2026

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
[Synchronization in a model of interacting inferior olive cells with variable electrotonic coupling]
Abstract:
Synchronization processes have been studied within the framework of a model describing the dynamics of two inferior olive cells coupled electrotonically through gap junctions surrounded by synaptic inhibitory terminals that block these couplings. A simple model of a chemical synaptic terminal based on the first-order kinetics has been constructed to describe the coupling break. It was found that different types of synchronous behavior exist in the system, depending on the parameters. These are 1:1 and 1:2 synchronization regimes, spike time binding, and others. It was demonstrated that even small changes in the coupling parameters (coupling strength and coupling break delay) may significantly affect the synchronous regimes of interacting cells. In some cases, the activity of one of inferior olive cells is suppressed due to collective dynamics, whereas the activity of the other cell is conserved.
Related Concept Videos
Propagation of Action Potentials
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
Electrical Synapses
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
Neural Circuits
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Junction Potentials in Galvanic Cells

