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Multiple intracerebral cavernous angiomas.

H Duong1, R del Carpio-O'Donovan, B Pike

  • 1Montreal Neurological Institute and Hospital, Que.

Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes
|October 1, 1991
PubMed
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Multiple brain cavernomas (angiomatosis cerebri) were incidentally found using MRI. This imaging technique is crucial for diagnosing and monitoring these vascular malformations, differentiating them from other conditions.

Area of Science:

  • Neuroradiology
  • Vascular Neurology

Background:

  • Multiple intracerebral cavernous angiomas (cavernomas), also termed angiomatosis cerebri, are rare vascular malformations.
  • Previous literature has described individual cases, but a series of this nature is not well-documented in radiology.

Purpose of the Study:

  • To report a series of eight patients with multiple cavernomas.
  • To evaluate the utility of high-field magnetic resonance imaging (MRI) in diagnosing and characterizing these lesions.

Main Methods:

  • High-field magnetic resonance imaging (MRI) was performed on eight patients with multiple cavernomas.
  • Clinical presentations including seizures, progressive neurologic deficit, and cerebral hemorrhage were noted.

Main Results:

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  • Multiplicity of cavernomas was an incidental finding on MRI in all eight patients.
  • MRI demonstrated characteristic features of cavernomas, though differentiation from other occult vascular malformations and hemorrhagic metastases is necessary.
  • Absence of edema, presence of calcifications, and temporal evolution on serial scans aid in differentiating cavernomas.

    • Conclusions:

    • High-field MRI is highly sensitive for detecting angiomatosis cerebri.
    • MRI's ability to visualize lesion evolution, including internal hemorrhage, makes it the preferred method for diagnosis and follow-up of cavernomas.