Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Operative management of pediatric radiation-induced cavernous malformations: insights from a single-center cohort.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same author

Molecular dynamics simulation of high slip flow of water confined between graphene nanochannels at experimentally accessible shear rates.

The Journal of chemical physics·2026
Same author

Management Strategies and Long-Term Outcomes of Pediatric Brainstem Cavernous Malformations: Conservative Management vs Surgery.

Neurosurgery·2026
Same author

Study of Arbitrarily Low Shear Rate Rheology Using Dissipative Particle Dynamics.

Journal of chemical theory and computation·2026
Same author

Management of pediatric patients with moyamoya arteriopathy and middle aortic syndrome: a retrospective single-institution case series.

Journal of neurosurgery. Pediatrics·2026
Same author

Understanding stroke risk phenotypes in pediatric patients with sickle cell disease and concurrent moyamoya arteriopathy: insights from 61 cases at a single institution.

Journal of neurosurgery. Pediatrics·2026
Same journal

Letter to the Editor. Enhancing comparability in idiopathic intracranial hypertension research through standardized outcome measures.

Neurosurgical focus·2026
Same journal

Introduction. Contemporary spinal arthroplasty.

Neurosurgical focus·2026
Same journal

Cervical disc arthroplasty as a safe and effective procedure for obese patients.

Neurosurgical focus·2026
Same journal

Comparing the operational metrics and functional outcomes of lumbar arthroplasty implants: a systematic review.

Neurosurgical focus·2026
Same journal

Long-term reoperation risk after cervical disc arthroplasty versus fusion: a level-matched meta-analysis of FDA investigational device exemption studies and international randomized trials.

Neurosurgical focus·2026
Same journal

Total disc replacement versus lumbar interbody fusion for degenerative disc disease: a meta-analysis of randomized controlled trials.

Neurosurgical focus·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2026

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
06:54

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

Introduction: moyamoya disease.

R Michael Scott1, Edward R Smith

  • 1Department of Neurosurgery, Children's Hospital, Boston, Massachusetts, USA.

Neurosurgical Focus
|April 2, 2009
PubMed
Summary
This summary is machine-generated.

Moyamoya disease was once misdiagnosed as arteritis. Advances in imaging and surgical techniques have improved the diagnosis and treatment of this rare cerebrovascular condition.

More Related Videos

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
08:22

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

Published on: July 21, 2013

A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion Without Damaging the Anatomical Structure of Cerebral Vessels
06:10

A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion Without Damaging the Anatomical Structure of Cerebral Vessels

Published on: May 17, 2024

Related Experiment Videos

Last Updated: Jun 24, 2026

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
06:54

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
08:22

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

Published on: July 21, 2013

A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion Without Damaging the Anatomical Structure of Cerebral Vessels
06:10

A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion Without Damaging the Anatomical Structure of Cerebral Vessels

Published on: May 17, 2024

Area of Science:

  • Neurology
  • Neurosurgery
  • Vascular Neurology

Background:

  • Moyamoya disease was poorly understood in the Western hemisphere until the late 20th century.
  • It was often misdiagnosed as arteritis due to similar clinical presentations and angiographic findings.
  • Early understanding lacked specific diagnostic criteria, leading to delayed or incorrect treatment.

Discussion:

  • The evolution of diagnostic tools, including catheter angiography, CT, and MR imaging, has been crucial.
  • These technologies allow for precise identification of the characteristic "puff of smoke" vascular changes.
  • Accurate diagnosis is essential for effective management and improved patient outcomes.

Key Insights:

  • Refined catheter angiography techniques significantly improved the visualization of moyamoya disease.
  • Computed Tomography (CT) and Magnetic Resonance (MR) imaging advancements clarified diagnostic significance.
  • The development of revascularization procedures transformed neurosurgical intervention for moyamoya.

Outlook:

  • Continued advancements in neuroimaging will further refine diagnostic accuracy.
  • Novel surgical techniques aim to improve revascularization efficacy.
  • Multidisciplinary approaches are essential for comprehensive moyamoya disease management.