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Related Experiment Video

Updated: Jun 24, 2026

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

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Published on: September 24, 2021

Fatal outcome in a pacemaker-dependent patient.

Manish Undavia¹, Avi Fischer, Davendra Mehta

¹Mount Sinai Medical Center, New York, New York 10029, USA. mundavia@aol.com

Pacing and Clinical Electrophysiology : PACE

|April 2, 2009

Summary

Medtronic Sprint Fidelis lead fractures caused controversy. A pacemaker-dependent patient died from lead fracture, highlighting limitations in current surveillance methods for implantable cardioverter-defibrillator leads.

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Area of Science:

Cardiology
Biomedical Engineering
Medical Device Safety

Background:

Medtronic Sprint Fidelis leads have faced scrutiny due to patient management controversies.
Current guidelines suggest device alerts and lead replacement upon detecting integrity breaches.

Observation:

A pacemaker-dependent patient with ischemic cardiomyopathy experienced cardiac arrest.
Postmortem interrogation revealed a fractured Medtronic Sprint Fidelis pace/sense lead.

Findings:

The patient's death was likely due to the fractured Sprint Fidelis lead.
Existing surveillance methods for lead integrity have demonstrated significant limitations.

Implications:

This case underscores the critical need for improved monitoring strategies for implantable cardioverter-defibrillator leads.
Re-evaluation of management protocols for patients with compromised leads is warranted to prevent adverse events.