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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Cells of the Epidermis01:24

Cells of the Epidermis

The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
Abrasion Resistance of Concrete01:23

Abrasion Resistance of Concrete

Abrasion resistance is an essential characteristic of concrete that determines its durability and longevity under various wear conditions. Concrete surfaces are vulnerable to different types of abrasion. For instance, surfaces may wear down due to the constant movement of vehicles or be eroded by solids carried in water, as seen in concrete canal linings. Specific tests are conducted to measure the abrasion resistance of concrete.
One such test is the revolving disc test, where three plates...
Layers of the Epidermis01:21

Layers of the Epidermis

The epidermis, the outermost layer of the skin, is composed of several distinct layers. From deep to superficial, the layers of the epidermis are as follows:
Stratum Basale
Stratum basale, also known as the stratum germinativum, is the deepest layer of the epidermis. It is composed of a single layer of actively dividing cells called basal cells or basal keratinocytes. These cells constantly undergo cell division to replenish the upper layers of the epidermis. Additionally, melanocytes, which...
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

Overview

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Related Experiment Video

Updated: Jun 24, 2026

An Epithelial Abrasion Model for Studying Corneal Wound Healing
04:45

An Epithelial Abrasion Model for Studying Corneal Wound Healing

Published on: December 29, 2021

Microabrasion: an epidermal abrasion.

Mark G Rubin

    Aesthetic Surgery Journal
    |April 2, 2009
    PubMed
    Summary

    Microabrasion is a mild skin resurfacing technique that exfoliates the epidermis for treating various skin concerns. Treatment outcomes depend on pressure, abrasive crystals, and technique.

    Area of Science:

    • Dermatology
    • Aesthetic Medicine

    Background:

    • Microabrasion is a superficial skin exfoliation procedure.
    • It targets epidermal layers for cosmetic improvement.

    Purpose of the Study:

    • To review the applications and outcomes of microabrasion.
    • To highlight factors influencing treatment results.

    Main Methods:

    • Review of microabrasion technique.
    • Discussion of parameters affecting outcomes.

    Main Results:

    • Microabrasion effectively treats dull texture, dyschromias, acne, and fine lines.
    • Variability in results is linked to pressure, crystal type, and operator skill.

    Conclusions:

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    Three Strategies to Induce Neurotrophic Keratitis and Nerve Regeneration in Murine Cornea
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    • Microabrasion offers a mild yet effective treatment option for specific dermatological conditions.
    • Optimizing technique and parameters is crucial for successful microabrasion outcomes.