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Related Concept Videos

Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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Related Experiment Video

Updated: Jun 24, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
03:47

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Hand rejuvenation.

Denton D Weiss, James H Carraway

    Aesthetic Surgery Journal
    |April 2, 2009
    PubMed
    Summary
    This summary is machine-generated.

    This study presents a multistage hand rejuvenation protocol targeting both skin and subcutaneous tissues. The innovative approach combines topical treatments, intense pulsed light, and autologous fat grafting for comprehensive anti-aging effects.

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    Published on: March 1, 2015

    Area of Science:

    • Dermatology and Plastic Surgery
    • Aesthetic Medicine
    • Regenerative Medicine

    Background:

    • Hand aging manifests as skin thinning, volume loss, and textural changes.
    • Previous rejuvenation methods often address only superficial skin layers.
    • A comprehensive approach is needed to address both skin and deeper tissue aging.

    Purpose of the Study:

    • To describe a multistage protocol for hand rejuvenation.
    • To evaluate the combined efficacy of topical therapies, intense pulsed light, and autologous fat grafting.
    • To achieve significant skin thickening, volume restoration, and textural improvement in aging hands.

    Main Methods:

    • Application of topical therapies and intense pulsed light (IPL) for skin enhancement.
    • Injection of autologous fat into multiple tissue layers for volume restoration.
    • Surgical excision of excess skin via a concealed ulnar incision.

    Main Results:

    • The protocol effectively thickens the skin and improves texture.
    • Age spots and leathery skin are visibly reduced.
    • Subcutaneous tissue is augmented, addressing volume deficits and creating a more youthful appearance.

    Conclusions:

    • This multistage hand rejuvenation protocol offers a comprehensive solution for aging hands.
    • Combining topical treatments, IPL, and fat grafting provides synergistic anti-aging benefits.
    • The procedure effectively rejuvenates both skin and subcutaneous tissues for improved aesthetics.