Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 24, 2026

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies
12:28

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies

Published on: March 12, 2022

An active contour model for segmenting and measuring retinal vessels.

Bashir Al-Diri1, Andrew Hunter, David Steel

  • 1Department of Computing and Informatics, University of Lincoln, Lincoln, UK.

IEEE Transactions on Medical Imaging
|April 2, 2009
PubMed
Summary

This study introduces a novel algorithm for retinal vessel segmentation and measurement using a "Ribbon of Twins" active contour model. The method achieves high accuracy in vessel edge detection and precise width measurements, outperforming existing benchmarks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retention in trials: a qualitative evidence synthesis of studies reporting participant reasons for trial non-completion.

BMJ open·2026
Same author

Direct access CT coronary angiography in patients referred with suspected cardiac chest pain: a novel patient pathway.

Open heart·2026
Same author

Existing research guidelines for inclusive trials methodology. Working toward the integration of qualitative research, equity, diversity, and inclusion and trials methodology: a focused mapping review.

Journal of clinical epidemiology·2026
Same author

Social Health Experiences and Support Needs of People Living With Young-Onset Dementia: A Qualitative Study.

Dementia (London, England)·2026
Same author

Inhomogeneity in electronic phase and flat band in magnetic kagome metal Co<sub>3</sub>Sn<sub>2</sub>S<sub>2</sub>.

Communications materials·2025
Same author

Optimising Psychosocial Interventions for Parents Following Perinatal Bereavement: A Qualitative Study of Midwives' Perspectives.

Journal of advanced nursing·2025

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Computer Vision

Background:

  • Accurate segmentation and measurement of retinal vessels are crucial for diagnosing and monitoring various eye diseases.
  • Existing algorithms face challenges with image noise, vessel width variations, and complex topological structures.

Purpose of the Study:

  • To develop and validate a robust algorithm for retinal vessel segmentation and width measurement.
  • To improve the accuracy and sensitivity of retinal vessel analysis compared to current methods.

Main Methods:

  • A
  • Ribbon of Twins
  • active contour model is employed for vessel edge detection, utilizing dual contour pairs for width consistency.
  • Initialization involves a generalized morphological order filter for centerline identification.

More Related Videos

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

Related Experiment Videos

Last Updated: Jun 24, 2026

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies
12:28

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies

Published on: March 12, 2022

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

  • An implicit neural cost function is used for resolving vessel junction configurations and network topology.

    • Main Results:

    • The algorithm demonstrates robustness in segmenting vessels under challenging conditions such as noise, blur, parallel vessels, and light reflex.
    • Achieved subpixel average width errors, indicating precise vessel width measurements.
    • Outperformed benchmark algorithms in segmentation sensitivity and measurement accuracy.

    Conclusions:

    • The proposed
    • Ribbon of Twins
    • algorithm offers a significant advancement in retinal vessel analysis.
    • It provides a reliable tool for accurate and sensitive retinal vessel segmentation and measurement, aiding in clinical diagnosis and research.