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Published on: November 6, 2019
Adenotonsillectomy and the development of overweight
Alet H Wijga1, Salome Scholtens, Marjan H Wieringa
1National Institute for Public Health and the Environment, Centre for Prevention and Health Services Research, PO Box 1, 3720 BA, Bilthoven, Netherlands. alet.wijga@rivm.nl
Insights
Children undergoing adenoidectomy and tonsillectomy face a higher risk of developing overweight. This surgery may trigger catch-up growth, leading to increased weight gain post-operation.
Area of Science:
- Pediatrics
- Otolaryngology
- Public Health
Background:
- Accelerated weight gain is observed post-adenoidectomy and tonsillectomy in patient studies.
- The role of adenoidectomy and tonsillectomy as a risk factor for developing overweight in the general population remains unclear.
Purpose of the Study:
- To investigate the association between adenoidectomy and tonsillectomy and the subsequent development of overweight.
- To determine if childhood adenoidectomy and tonsillectomy increase the risk of developing overweight.
Main Methods:
- A cohort of 3963 children from the Dutch Prevention and Incidence of Asthma and Mite Allergy birth cohort was analyzed.
- Data on weight, height, surgical history (adenoidectomy and tonsillectomy), and covariates were collected via annual parental questionnaires and investigator measurements at age 8.
Main Results:
- Adenoidectomy and tonsillectomy between ages 0-7 were significantly linked to overweight and obesity at age 8.
- Pre-existing overweight at age 2 did not increase the risk of later adenoidectomy and tonsillectomy, ruling out reverse causality.
- Longitudinal data suggest surgery acts as a turning point, shifting growth from faltering to catch-up, potentially explaining increased overweight risk.
Conclusions:
- Children who undergo adenoidectomy and tonsillectomy are at an elevated risk for developing overweight in the years following surgery.
- The findings highlight a critical period of growth alteration after adenoidectomy and tonsillectomy, impacting long-term weight status.
Objective:
Studies among patients have shown accelerated weight gain after (adeno)tonsillectomy. Whether (adeno)tonsillectomy is also a risk factor for the development of overweight is unknown. We investigated the association between (adeno)tonsillectomy and the subsequent development of overweight in the general population.
Methods:
The study population consisted of 3963 children participating in the Dutch Prevention and Incidence of Asthma and Mite Allergy birth cohort. Data on weight and height, adenoidectomy and tonsillectomy, and covariates (gender, birth weight, maternal education, maternal overweight, maternal smoking during pregnancy, breastfeeding, and smoking in the home) were obtained from annual questionnaires completed by the parents. In addition to the questionnaire data, weight and height were measured by the investigators when the children were 8 years old.
Results:
(Adeno)tonsillectomy between 0 and 7 years of age was significantly associated with overweight and obesity at age 8. Overweight at the age of 2 years was not associated with increased risk of (adeno)tonsillectomy in later years, indicating that the association between (adeno)tonsillectomy and overweight was not explained by preexisting overweight. Longitudinal data on weight and height in the years before and after surgery suggest that (adeno)tonsillectomy forms a turning point between a period of growth faltering and a period of catch-up growth, which might explain the increased risk to develop overweight after the operation.
Conclusion:
Children who undergo (adeno)tonsillectomy are at increased risk to develop overweight in the years after surgery.
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