Anterior segment necrosis associated with endogenous endophthalmitis secondary to group C streptococcal septicemia

Anterior segment necrosis following ocular infections and endophthalmitis secondary to group C streptococcal infection are both rare. We report a case of unilateral anterior segment necrosis associated with bilateral metastatic group C streptococcal endophthalmitis in a 68-year-old black man with multiple systemic disorders complicated by culture-confirmed group C streptococcal septicemia and endocarditis. Pathological examination of the left eye at autopsy demonstrated necrosis of the anterior segment involving the cornea, iris, lens and ciliary body. The right eye showed signs of mild residual inflammation. To our knowledge anterior segment necrosis has not previously been described in association with group C streptococcal endophthalmitis.