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Related Experiment Video

Updated: Jun 24, 2026

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum
07:50

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

Published on: December 8, 2023

Two new lignans from Schisandra henryi.

Hai-Tao Liu1, Li-Jia Xu, Yong Peng

  • 1Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.

Chemical & Pharmaceutical Bulletin
|April 2, 2009
PubMed
Summary
This summary is machine-generated.

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Researchers isolated two novel lignans, henricines A and B, and eight known lignans from Schisandra henryi stems. Their structures were determined using advanced spectral analysis techniques, including NMR.

Area of Science:

  • Natural Product Chemistry
  • Organic Chemistry
  • Phytochemistry

Background:

  • Schisandra henryi is a plant species with a history of traditional medicinal use.
  • Lignans are a diverse class of natural compounds found in plants, known for various biological activities.
  • Previous research has identified several lignans from the Schisandra genus.

Purpose of the Study:

  • To isolate and characterize new lignan compounds from the stems of Schisandra henryi.
  • To contribute to the understanding of the chemical diversity within the Schisandra genus.

Main Methods:

  • Phytochemical investigation of Schisandra henryi stem extracts.
  • Isolation of compounds using chromatographic techniques.
  • Structure elucidation of isolated compounds via comprehensive spectral analysis, including 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy.

Related Experiment Videos

Last Updated: Jun 24, 2026

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum
07:50

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

Published on: December 8, 2023

Main Results:

  • Two new lignans, designated henricines A (1) and B (2), were successfully isolated.
  • Eight known lignans, including ganshisandrine (3), wulignan A(2) (4), epiwulignan A(1) (5), deoxyschisandrin (6), wulignan A(1) (7), epischisandrone (8), schisantherin A (9), and schisandrol A (10), were also identified.
  • The structures of the novel compounds were confirmed through detailed analysis of NMR data.

Conclusions:

  • The chemical investigation of Schisandra henryi stems yielded two new lignans and eight known lignans.
  • The findings expand the known phytochemical profile of Schisandra henryi and contribute to the library of natural lignans.
  • This study highlights the potential of Schisandra species as a source of structurally diverse lignans.