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Gamma knife radiosurgery for intraventricular meningiomas
In-Young Kim1, Douglas Kondziolka, Ajay Niranjan
1Department of Neurological Surgery, Center for Image-Guided Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA.
Acta Neurochirurgica
|April 2, 2009
Summary
Gamma Knife Radiosurgery (GKR) offers a minimally invasive option for intraventricular meningiomas. This study found GKR achieved tumor control in 7 of 9 patients, with no hydrocephalus or treatment morbidity.
Area of Science:
- Neurosurgery
- Radiation Oncology
Background:
- Intraventricular meningiomas are rare tumors.
- Stereotactic radiosurgery is a minimally invasive treatment option.
Purpose of the Study:
- To report the experience using Gamma Knife Radiosurgery (GKR) for intraventricular meningiomas.
Main Methods:
- Retrospective review of 9 patients treated with GKR over 16 years.
- GKR used as primary management in 5 patients, for recurrent tumors in 3, and adjunctive in 1.
- Median tumor volume was 3.9 cc, with a median margin dose of 16.0 Gy.
Main Results:
- Average follow-up was 64 months.
- Tumor control achieved in 7 of 9 patients; 4 tumors regressed, 2 remained unchanged.
- No hydrocephalus or treatment-related morbidity observed.
Conclusions:
- GKR is a viable minimally invasive option for intraventricular meningiomas.
- Suitable for patients unsuitable for or failing resection.
