Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gene mapping in cancer.

L A Cannizzaro1

  • 1Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania.

Cancer Genetics and Cytogenetics
|September 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of t(11;19)(q23;p13.3) by fluorescence in situ hybridization analysis in a pediatric patient with therapy-related acute myelogenous leukemia.

Cancer genetics and cytogenetics·2001
Same author

Atypical endometrial hyperplasia shares genomic abnormalities with endometrioid carcinoma by comparative genomic hybridization.

Human pathology·2001
Same author

Identical clonal origin of synchronous and metachronous low-grade, noninvasive papillary transitional cell carcinomas of the urinary tract.

Human pathology·1999
Same author

Essential role of STAT3 for embryonic stem cell pluripotency.

Proceedings of the National Academy of Sciences of the United States of America·1999
Same author

FHIT gene transcript alterations occur frequently in myeloproliferative and myelodysplastic diseases.

Cytogenetics and cell genetics·1998
Same author

Clonal chromosome aberrations with monosomy of chromosome 8 in a case of grade III chondrosarcoma.

Cancer genetics and cytogenetics·1997
Same journal

Letter to the editor regarding the article "Chromosome abnormalities additional to the Philadelphia chromosome at the diagnosis of chronic myelogenous leukemia: pathogenic and prognostic implications".

Cancer genetics and cytogenetics·2010
Same journal

A novel t(10;12)(q21;p13) involving ETV6 in a patient with acute myeloid leukemia.

Cancer genetics and cytogenetics·2010
Same journal

A case of acute myeloid leukemia initially treated as chronic lymphocytic leukemia: what do we know about t(4;12)(q12;p13)?

Cancer genetics and cytogenetics·2010
Same journal

Myelodysplastic syndrome with isochromosome 5p and trisomy 8 after treatment of a multiple myeloma.

Cancer genetics and cytogenetics·2010
Same journal

Chromosomal imbalances in urinary bladder paraganglioma.

Cancer genetics and cytogenetics·2010
Same journal

A pericentric inv(9)(p22q34) of the der(9)t(9;22)(q34;q11.2) is a recurrent secondary anomaly in Ph-positive leukemia.

Cancer genetics and cytogenetics·2010
See all related articles

Identifying genetic alterations in cancer is crucial. New molecular tools help pinpoint cancer-associated genes, aiding in understanding tumor development and improving cancer diagnostics.

Area of Science:

  • Genetics
  • Oncology
  • Molecular Biology

Background:

  • Consistent genetic alterations are observed in specific cancer types and stages.
  • Understanding these alterations is key to cancer research.

Purpose of the Study:

  • To explore volatile regions of the human genome associated with cancer.
  • To investigate the functional role of genomic areas in leukemia and solid tumor development.

Main Methods:

  • Utilizing powerful molecular cytogenetic and genetic methods.
  • Applying advanced techniques to analyze human genome regions.
  • Combining new tools with cytogenetics and somatic cell genetics.

Main Results:

  • Localization of potential cancer-associated genes.

Related Experiment Videos

  • Detailed analysis of genomic areas implicated in cancer.
  • Isolation and dissection of newly discovered cancer genes.

    • Conclusions:

    • Molecular cytogenetic tools are vital for cancer gene discovery.
    • These methods enhance the understanding of cancer initiation and progression.
    • Combined approaches yield essential DNA markers for cancer diagnostics and prognostics.