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Updated: Jun 24, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
[Knowledge of human papilloma virus-associated disease among women in general practice]
Lone Kjeld Petersen1, Jesper Nielsen, Hanne Vaesel
1Sanofi Pasteur MSD, Parallelvej 12, DK-2800 Lyngby.
Introduction:
Cervical cancer is caused by oncogenic human papilloma virus (HPV) serotypes. Types 16 and 18 are responsible for approximately 75% of all cases in Europe. Low-malignant serotypes like HPV 6 and 11 are the cause of approximately 90% of all cases of conyloma accuminata. Approximately 75% of the adult population has or will become infected by one or more HPV serotypes. The purpose of the study was to investigate the level of knowledge of the cause of cervical cancer, cervical dysplasia and condylomas among women seen in Danish general practice, and to investigate the women's expectations to communication with regard to prophylactic initiatives and, finally, to determine which aspects would influence their wish for HPV-vaccination.
Material And Methods:
Patient questionnaire in 26 general practices between September 2006 through February 2007.
Results:
A total of 425 women aged 14-39 years were included in the study. Only 1.2% of the women correctly stated HPV as the cause of cervical cancer and 0.7% stated HPV as the cause of condylomas. In all, 96.2% thought that general practitioners should actively inform their patients of prophylactic initiatives such as vaccination against cervical cancer. Among all women, 96.4% considered HPV-vaccination.
Conclusion:
In this population, knowledge about the cause of cervical cancer and condylomas was limited. There was a clear wish - and expectation - to be actively informed on prophylactic initiatives by the general practitioner.
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