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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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Related Experiment Video

Updated: Jun 24, 2026

Transient Treatment of Human Pluripotent Stem Cells with DMSO to Promote Differentiation
06:55

Transient Treatment of Human Pluripotent Stem Cells with DMSO to Promote Differentiation

Published on: July 17, 2019

DMSO: applications in plastic surgery.

V Leroy Young, C B Boswell, Robert F Centeno

    Aesthetic Surgery Journal
    |April 3, 2009
    PubMed
    Summary

    Dimethyl sulfoxide (DMSO) can improve blood flow and treat ischemia in surgical flaps. Topical application every 4-6 hours is recommended for affected areas to enhance tissue perfusion.

    Area of Science:

    • Plastic Surgery
    • Dermatology
    • Regenerative Medicine

    Background:

    • Ischemia in surgical flaps compromises tissue viability.
    • Dimethyl sulfoxide (DMSO) is explored for its potential therapeutic properties.

    Purpose of the Study:

    • To evaluate the efficacy of topical dimethyl sulfoxide (DMSO) in treating ischemia in surgical flaps.
    • To explore additional cosmetic applications of DMSO.

    Main Methods:

    • Application of topical dimethyl sulfoxide (DMSO) to ischemic flap areas.
    • Monitoring of tissue perfusion and blood flow improvement.

    Main Results:

    • Dimethyl sulfoxide (DMSO) demonstrated an increase in tissue perfusion.
    • DMSO may effectively treat or prevent ischemia in flaps.

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    Conclusions:

    • Topical DMSO application is a recommended treatment for flap ischemia.
    • Further applications in cosmetic surgery include skin care, pain relief, and keloid treatment.