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Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats
Published on: March 17, 2019
A pilot study of impulsivity and compulsivity in pathological gambling
Carlos Blanco1, Marc N Potenza, Suck Won Kim
1Department of Psychiatry, Columbia University, New York, NY 10032, United States. cb255@columbia.edu
Psychiatry Research
|April 3, 2009
Summary
Impulsivity, not obsessionality, is the primary driver of pathological gambling (PG) severity. Treatment changes in gambling severity are linked to changes in impulsivity, independent of paroxetine.
Area of Science:
- Psychiatry
- Behavioral Science
- Neuroscience
Background:
- Pathological gambling (PG) is a complex disorder.
- Its relationship with impulsivity and obsessionality/compulsivity requires further investigation.
- Understanding these relationships can inform treatment strategies.
Purpose of the Study:
- To examine the relationship between gambling severity, impulsivity, and obsessionality/compulsivity in pathological gamblers.
- To assess the impact of treatment on these variables.
- To determine the predominant factor influencing gambling severity.
Main Methods:
- Utilized Pearson correlations and linear regression models.
- Analyzed data from 38 pathological gamblers in a randomized, placebo-controlled trial.
- Assessed gambling severity using the Pathological Gambling Modification of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS).
- Measured impulsivity with the Eysenck Impulsiveness Questionnaire (EIQ) and obsessionality/compulsivity with the Padua Inventory (PI).
Main Results:
- At baseline, PG-YBOCS scores significantly correlated with EIQ Impulsiveness and PI factors I and IV.
- These associations were not significant after adjusting for impulsivity.
- No significant differences in PG-YBOCS changes were observed between paroxetine and placebo groups.
- Changes in PG-YBOCS scores post-treatment correlated with changes in impulsivity scores, independent of paroxetine.
Conclusions:
- Pathological gambling exhibits features of both obsessionality/compulsivity and impulsivity.
- Impulsivity appears to be the predominant factor influencing gambling severity.
- Changes in gambling severity during treatment are most strongly associated with changes in impulsivity.

