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Validation of the Dutch guidelines for dual X-ray absorptiometry measurement
Noortje A Verdijk1, Arnold C Romeijnders, Jos J Ruskus
1The Centre of Research for Psychology in Somatic diseases, Medical Psychology and Neuropsychology, Tilburg University, Tilburg, the Netherlands. n.a.verdijk@uvt.nl
Background:
In Europe, a case-finding strategy for osteoporosis is recommended above widespread population-based screening. However, no universally accepted policy currently exists. In 2005, the Dutch College of General Practitioners published guidelines for GPs to select patients for dual energy X-ray absorptiometry (DXA).
Aim:
To evaluate the sensitivity, specificity, and predictive value of the Dutch guidelines to select participants with osteoporosis for DXA.
Design Of Study:
Cross-sectional.
Setting:
A total of 345 females aged over 50 years (mean age = 62 years, standard deviation [SD] = 8.3) and 99 males over 65 years of age (mean age = 72 years, SD = 5.2) of a Dutch general practice.
Method:
Calculation of sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the Dutch case-finding instrument for selecting patients with osteoporosis for DXA measurement.
Results:
Sensitivity was 19.5%, specificity 85.6%, PPV 18.6%, and NPV 86.6%.
Conclusion:
The Dutch guidelines are unreliable in detecting people at risk for osteoporosis.
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