Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...

Cardiopulmonary Resuscitation III: AED Use

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...

Cardiopulmonary Resuscitation IV: Pharmacological Management

Cardiopulmonary Resuscitation IV: Pharmacological Management

Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...

Dysrhythmias VII: Nursing Management of Dysrhythmias

Dysrhythmias VII: Nursing Management of Dysrhythmias

Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...

Pulse rhythm

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Antimicrobial resistance and biofilm formation of penile prosthesis isolates: insights from in-vitro analysis.

The journal of sexual medicine·2025

Same author

Understanding general public and healthcare provider knowledge gaps in male factor infertility.

Translational andrology and urology·2025

Same author

Reply to Editorial Comment on "Routine Sperm Cryopreservation Before Vasectomy Is not Cost-effective and Does not Increase Live Birth Rates Compared to Surgical Sperm Retrieval or Vasectomy Reversal".

Urology·2025

Same author

Routine Sperm Cryopreservation Before Vasectomy Is not Cost-effective and Does not Increase Live Birth Rates Compared to Surgical Sperm Retrieval or Vasectomy Reversal.

Urology·2025

Same author

Hyaluronic acid and urology: a systematic review and meta-analysis.

Sexual medicine reviews·2024

Same author

Associations Between Sodium-Glucose Co-transporter 2 Inhibitors and Urologic Diseases: Implications for Lower Urinary Tract Symptoms From a Multi-State Health System Analysis.

Urology·2024

Search research articles

Related Experiment Video

Updated: Jun 24, 2026

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice

Published on: June 29, 2022

Optimization of feedback pacing for defibrillation.

Steffan Puwal¹, Bradley J Roth

¹Department of Physics, Oakland University, Rochester, MI 48309, USA.

IEEE Transactions on Bio-Medical Engineering

|April 4, 2009

Summary

This summary is machine-generated.

Optimizing electrode spacing in multisite feedback pacing for defibrillation significantly improves success rates. Maximum defibrillation success reached 88% with widely spaced electrodes, compared to 26% with a single electrode.

More Related Videos

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Published on: August 26, 2021

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

Related Experiment Videos

Last Updated: Jun 24, 2026

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice

Published on: June 29, 2022

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Published on: August 26, 2021

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

Area of Science:

Biomedical Engineering
Computational Physiology
Cardiac Electrophysiology

Background:

Defibrillation is critical for treating life-threatening cardiac arrhythmias.
Multisite feedback pacing offers a potential strategy to improve defibrillation efficacy.
Optimizing pacing parameters, such as electrode configuration, is essential for maximizing success.

Purpose of the Study:

To optimize a mathematical model for multisite feedback pacing in defibrillation.
To determine the impact of electrode spacing and stimulus period on defibrillation success.
To identify optimal electrode configurations for maximizing defibrillation outcomes.

Main Methods:

Development and optimization of a mathematical model for multisite feedback pacing.
Simulation of defibrillation scenarios using varying electrode spacing and stimulus periods.
Analysis of defibrillation success rates based on model outputs.

Main Results:

The highest defibrillation success rate achieved was 88% with four electrodes spaced maximally apart.
A single electrode configuration yielded a significantly lower optimum success rate of 26%.
Electrode spacing was identified as a critical parameter influencing pacing effectiveness.

Conclusions:

Widely spaced electrode configurations are superior for multisite feedback pacing in defibrillation.
Mathematical modeling provides valuable insights for optimizing defibrillation strategies.
Further research into electrode placement and pacing protocols can enhance cardiac rhythm management.