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Need for thiamine in peripheral parenteral nutrition after abdominal surgery in children

Kouji Masumoto1, Genshiro Esumi, Risa Teshiba

  • 1Department of Pediatric Surgery, Reproductive and Developmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. kmasu@pedsurg.med.kyushu-u.ac.jp

JPEN. Journal of Parenteral and Enteral Nutrition
|April 4, 2009
PubMed

Insights

Pediatric patients receiving parenteral nutrition after surgery may need thiamine. Supplementing thiamine in parenteral nutrition prevents deficiency during postoperative starvation in children.

Area of Science:

  • Pediatric Surgery
  • Nutritional Support
  • Biochemistry

Background:

  • Thiamine levels fluctuate in pediatric patients on parenteral nutrition post-surgery.
  • The necessity of thiamine supplementation in pediatric patients receiving parenteral nutrition after surgery is not well-established.

Purpose of the Study:

  • To determine if pediatric patients require thiamine supplementation when receiving parenteral nutrition post-abdominal surgery.

Main Methods:

  • A prospective study involving 15 pediatric patients undergoing abdominal surgery.
  • Patients were divided into two groups: one receiving parenteral nutrition with thiamine, the other without.
  • Thiamine blood concentrations were monitored preoperatively and daily from postoperative day 1 to 5.

Main Results:

  • All patients had normal preoperative thiamine levels.
  • Thiamine concentrations decreased over time in patients not receiving thiamine supplementation.
  • Three out of seven patients (43%) not receiving thiamine showed levels below normal by postoperative day 5.

Conclusions:

  • Thiamine blood concentrations decline in pediatric patients receiving parenteral nutrition without thiamine post-abdominal surgery.
  • Clinicians should consider adding thiamine to parenteral nutrition solutions for pediatric patients during short-term postoperative starvation.
Abstract

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