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Published on: December 30, 2016
Crystallization and preliminary crystallographic studies of Helicobacter pylori HugZ, a novel haem oxygenase
Fan Jiang1, Yonglin Hu, Ying Guo
1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, People's Republic of China.
Abstract:
The haem oxygenase HugZ is part of the iron-acquisition mechanism that is essential for the adaptive colonization of Helicobacter pylori, a major pathogen of gastroenteric diseases. The HugZ-haemin complex has been purified and crystallized and diffraction data sets have been collected to 1.8 A resolution. The HugZ-haemin complex crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 88.40, b = 139.37, c = 152.97 A.
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