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Arrhythmias after the Fontan procedure. Comparison of total cavopulmonary connection and atriopulmonary connection
1Cardiothoracic Unit, Hospital for Sick Children, London, UK.
Insights
Total cavopulmonary connection (TCPC) shows lower early arrhythmia and mortality rates compared to atriopulmonary connection (APC) in pediatric heart surgery patients. This suggests TCPC may be a safer surgical option for complex congenital heart defects.
Area of Science:
- Cardiology
- Pediatric Cardiac Surgery
- Electrophysiology
Background:
- Atriopulmonary connection (APC) and total cavopulmonary connection (TCPC) are surgical procedures for complex congenital heart defects.
- Arrhythmia is a potential complication following these cardiac surgeries.
Purpose of the Study:
- To compare the incidence of arrhythmia and associated mortality between APC and TCPC.
- To evaluate the long-term outcomes of arrhythmia in patients who underwent either APC or TCPC.
Main Methods:
- A retrospective comparison of 40 patients undergoing APC and 40 patients undergoing TCPC between 1986 and 1990.
- Analysis of pre-operative, early post-operative, and long-term follow-up (ambulatory ECG) arrhythmia data.
- Comparison of hospital mortality and arrhythmia-related mortality between the two groups.
Main Results:
- Hospital mortality was significantly higher after APC (15/40) compared to TCPC (6/40).
- Early post-operative atrial flutter (AFL) was more frequent and associated with higher mortality after APC (9 cases, 8 deaths) versus TCPC (2 cases, 0 deaths).
- Long-term arrhythmia incidence and mortality were comparable between the groups, though early outcomes favored TCPC.
Conclusions:
- Total cavopulmonary connection (TCPC) is associated with lower early postoperative arrhythmia and mortality compared to atriopulmonary connection (APC).
- TCPC appears to be a safer initial surgical approach, particularly in patients with complex cardiac defects.
- Further investigation into long-term electrophysiological outcomes may be warranted for both procedures.
Abstract:
Arrhythmia was compared between 40 consecutive patients (pts) undergoing atriopulmonary connection (APC) and 40 undergoing total cavopulmonary connection (TCPC), between 1986 and 1990. Patients were not randomized, and those undergoing APC predominantly had tricuspid atresia (57.5% versus 15%) compared with pts undergoing TCPC who had more varied and complex cardiac defects. Before surgery there was no significant arrhythmia in either group. Hospital mortality was 15/40 and 6/40 for APC and TCPC, respectively (p less than 0.05). Early after APC nine pts developed atrial flutter (AFL) and eight died, while after TCPC only two developed AFL, and neither died (p less than 0.01). Fatal junctional ectopic tachycardia occurred in one pt in each group. During follow-up (38 +/- 8.5 months after APC versus 20 +/- 10 months after TCPC), new arrhythmia was uncommon (two AFL after APC with one death versus two AFL and one supraventricular tachycardia after TCPC with no deaths). Ambulatory ECG during follow-up showed arrhythmia in two APC and six TCPC pts (p = NS). The incidence of early arrhythmia and mortality associated with early arrhythmia appears to be less after TCPC compared with APC.
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