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Updated: Jun 24, 2026

Fluorescence detection methods for microfluidic droplet platforms
Published on: December 10, 2011
A fluorescence turn-on detection of cyanide in aqueous solution based on the aggregation-induced emission
Lihua Peng1, Ming Wang, Guanxin Zhang
1Beijing National Laboratory for Molecular Sciences, Organic Solids Laboratory, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Abstract:
The nucleophilic addition of cyanide to the trifluoroacetylamino group in 2 yields an amphiphilic species which would induce the aggregation of silole 1, and as a result, the fluorescence of the ensemble increases largely. Accordingly, a fluorescence turn-on detection of cyanide in aqueous solution can be established with the ensemble of silole 1 and compound 2. Also, this ensemble displays good selectivity toward cyanide over other common inorganic anions.
