Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sex Linked Disorders01:43

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Psychosexual Theory of Development01:14

Psychosexual Theory of Development

Sigmund Freud's psychosexual theory of development suggests that early childhood experiences significantly shape personality and behavior. Freud proposed that development is discontinuous, occurring in five distinct stages, each defined by a focus on different erogenous zones. He believed that failure to resolve the conflicts specific to each stage successfully could result in fixation, potentially influencing behavior as adults.
The Five Stages of Psychosexual Development
Freud's psychosexual...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
Development of the Sexual Organs in the Embryo and Fetus01:15

Development of the Sexual Organs in the Embryo and Fetus

Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychiatric disorder diagnoses and adverse psychiatric outcomes among pregnant and postpartum adolescents in Ontario, Canada: a retrospective, population-based cohort study.

The Lancet. Child & adolescent health·2026
Same author

The role of the dental profession in supporting families who experience food insecurity: a patient and public involvement strategy for a qualitative study.

British dental journal·2026
Same author

Beyond the scalpel: redefining surgical training for tomorrow: Canadian Conference for the Advancement of Surgical Education, Oct. 16-17, 2025 Winnipeg, Manitoba.

Canadian journal of surgery. Journal canadien de chirurgie·2026
Same author

Trends in Pediatric Benign Ovarian Surgery and Risk of Subsequent Ovarian Surgery: An Ontario Population-Based Study.

Journal of pediatric and adolescent gynecology·2026
Same author

Improving resource stewardship in post-pandemic primary care: Insights into choosing Wisely Canada guidelines.

Canadian journal of rural medicine : the official journal of the Society of Rural Physicians of Canada = Journal canadien de la medecine rurale : le journal officiel de la Societe de medecine rurale du Canada·2026
Same author

Hysterectomy for placenta accreta spectrum disorder: Impact of institutional surgical volume on patient outcomes.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2026

Related Experiment Video

Updated: Jun 24, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Disorders of sexual development.

Lisa Allen1

  • 1Section of Pediatric Gynecology, Division of Endocrinology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada. lallen@mtsinai.on.ca

Obstetrics and Gynecology Clinics of North America
|April 7, 2009
PubMed
Summary

Disorders of sex development (DSD) involve variations in sex characteristics. This review focuses on diagnosing and managing ambiguous genitalia in infants, including surgical and disclosure approaches.

Area of Science:

  • Medical science
  • Pediatrics
  • Endocrinology

Background:

  • Disorders of Sex Development (DSD) encompass conditions where chromosomal, gonadal, or anatomical sex development deviates from typical patterns.
  • These variations can lead to incongruence between different aspects of sex development.
  • Ambiguous genitalia in newborns presents complex challenges for medical professionals and families.

Purpose of the Study:

  • To review the diagnostic and management strategies for infants with disorders of sex development and ambiguous genitalia.
  • To discuss the evolution of surgical policies and the impact of long-term outcome studies.
  • To present a framework for developmental approaches to disclosure for affected children and families.

Main Methods:

  • Review of current medical and surgical management practices for DSD.

More Related Videos

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

Related Experiment Videos

Last Updated: Jun 24, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

  • Analysis of evolving surgical techniques and outcomes.
  • Examination of diagnostic approaches in the newborn period.
  • Discussion of interprofessional team collaboration in DSD care.
  • Main Results:

    • Management of DSD requires an interprofessional team approach, emphasizing timely diagnosis and appropriate gender assignment.
    • Surgical interventions for DSD have evolved, with ongoing research into long-term outcomes.
    • Developmental considerations are crucial for disclosure and ongoing support.

    Conclusions:

    • Effective management of DSD necessitates a multidisciplinary approach, integrating medical, surgical, and psychosocial aspects.
    • Continued research on long-term outcomes is vital for refining treatment strategies.
    • A sensitive, developmental approach to disclosure is essential for the well-being of individuals with DSD.